Tyrvaya is a prescription nasal spray used to treat the signs and symptoms of dry eye disease

See the results for yourself. Check out the Tyrvaya® (varenicline solution) nasal spray clinical trial results.

Real relief, real fastwhat does rapid relief look & feel like?

Tyrvaya was put to the test in two 28-day clinical trials of people with dry eye. In both studies, Tyrvaya significantly increased tear production in nearly 50% of patients at 4 weeks, vs in 14% and 28% of patients with placebo, when used twice a day, ~12 hours apart. Use of artificial tears was allowed.

See rapid results

On average, Tyrvaya increased real tear production in as early as ~5 minutes after just 1 dose

Feel symptoms improve quickly

People using Tyrvaya had less eye dryness at 4 weeks and as early as 3 weeks in 1 out of 2 clinical trials

Get significant results

Tyrvaya increased the amount of real tears produced on average after 4 weeks of consistent use

Individual results may vary.

2x day

Remember—in order to get the benefits of your own real tears,
Tyrvaya needs to be used every day, twice a day, ~12 hours apart.

Drops weren't
enough for Crystal

View transcript

I started noticing a difference in the way that my eyes felt within a few weeks.-Crystal, a real Tyrvaya patient
Individual results may vary.

The patient featured in this video is a paid consultant for Viatris.

Dry eye reality check

If dry eye is always on your mind, then you should be thinking about other ways to get lasting relief. It's time to ask your doctor about trying Tyrvaya.

What to expect when using Tyrvaya

In clinical trials, Tyrvaya was shown to be well tolerated. The most common side effects included:

82%

sneezing

16%

cough

13%

throat
irritation

8%

nose
irritation

The majority of side effects were mild. No serious side effects related to Tyrvaya were reported in clinical trials.

With Tyrvaya, sneezing was mild:

98%

98% of people who sneezed after using Tyrvaya rated the side effect as mild.

1 min

Most said sneezing stopped after 1 minute, and none were bothered enough by it to discontinue the trial.

Tell your doctor if you are pregnant or plan to become pregnant, are breastfeeding, or are planning to breastfeed. It is not known if Tyrvaya will harm your unborn baby or pass into breast milk. You and your doctor should decide if you will use Tyrvaya if you plan to breastfeed.

Forget what you know about other nasal sprays

Have questions about Tyrvaya?

Contact us

Important Safety Information

What are the possible side effects of Tyrvaya?

The most common side effects of Tyrvaya include sneezing, cough, and throat and nose irritation.

Important information you need to know before using Tyrvaya

Tyrvaya is for use in the nose.
Do not shake the bottles.

What is Tyrvaya® (varenicline solution)?

Tyrvaya is a prescription nasal spray used to treat the signs and symptoms of dry eye disease.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1‑800‑FDA‑1088.

For additional safety information, click here for Patient Information and the Instructions for Use and discuss with your doctor.

Important Safety Information

What are the possible side effects of Tyrvaya?

The most common side effects of Tyrvaya include sneezing, cough, and throat and nose irritation.

Important information you need to know before using Tyrvaya

Tyrvaya is for use in the nose.
Do not shake the bottles.

What is Tyrvaya® (varenicline solution)?

Tyrvaya is a prescription nasal spray used to treat the signs and symptoms of dry eye disease.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1‑800‑FDA‑1088.

For additional safety information, click here for Patient Information and the Instructions for Use and discuss with your doctor.